Escherichia-Virus T3
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Escherichia-Virus T3, Bakteriophage T3 (oder der T3-Phage, offiziell Escherichia virus T3) ist eine Virus-Spezies der Gattung Teetrevirus in der Familie Autographiviridae (Unterfamilie Studiervirinae). Viren dieser Spezies (Art) sind in der Lage, anfällige Bakterienzellen zu infizieren, einschließlich Stämme von Escherichia coli. Die Spezies wird daher unter den Bakteriophagen, speziell Coliphagen, klassifiziert.
Aufbau und Assemblierung (Zusammenbau) von Virionen bei den Phagen T3 und T7, beide in der Unterfamilie Studiervirinae (Familie Autographiviridae). Capsid I = Prokapsid, Capsid II = reife Kapsidform, die mit DNA befüllt wird.[2]
Dieser Phage ist in seiner Struktur eng mit dem Escherichia-Virus T7 (T7-Phage) verwandt,[3] obwohl sich die beiden Viren in der Kapsidreifung unterscheiden können.[4] Details, insbesondere zu den beobachteten larger-than-phage black particles (LBPs), finden sich bei Serwer et al. (2020).[2]
Einzelnachweise
- ↑ a b c d ICTV: ICTV Master Species List 2019.v1, New MSL including all taxa updates since the 2018b release, March 2020 (MSL #35)
- ↑ a b Philip Serwer, Barbara Hunter, Elena T. Wright: Electron Microscopy of In-Plaque Phage T3 Assembly: Proposed Analogs of Neurodegenerative Disease Triggers, in: MDPI Pharmaceuticals, Band 13, Nr. 1, 18. Januar 2020, 18; doi:10.3390/ph13010018
- ↑ D. Fraser, R. C. Williams: Details of frozen-dried T3 and T7 bacteriophages as shown by electron microscopy. In: Journal of Bacteriology. 65, Nr. 2, Februar 1953, S. 167–70. PMID 13034710. PMC 169660 (freier Volltext).
- ↑ Philip Serwer, E. T. Wright, K. Hakala, S. T. Weintraub, M. Su, W. Jiang: DNA packaging-associated hyper-capsid expansion of bacteriophage t3.. In: Journal of Molecular Biology. 397, Nr. 2, 26. März 2010, S. 361–374. doi:10.1016/j.jmb.2010.01.058. PMID 20122936. PMC 2848125 (freier Volltext).
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Autor/Urheber: Philip Serwer, Barbara Hunter, Elena T. Wright, Lizenz: CC BY-SA 4.0
DNA packaging of the related phages, T3 and T7 (Escherichia virus T3 and Escherichia virus T7 respectively). Capsid I (left image) is assembled and then starts to package DNA while converting to capsid II (next image) and ultimately becomes a phage particle capsid (right image). The particles investigated here are dynamic capsid II expansion products that potentially mature to become capsids of phages; arrows in the third image from the left indicate expansion/contraction dynamism. Although pictured here as intermediates, intermediate status has not been biochemically demonstrated for particles generated by shell dynamism.
Autor/Urheber: Philip Serwer, Barbara Hunter, Elena T. Wright, Lizenz: CC BY-SA 4.0
DNA packaging of the related phages, T3 and T7 (Escherichia virus T3 and Escherichia virus T7 respectively). Capsid I (left image) is assembled and then starts to package DNA while converting to capsid II (next image) and ultimately becomes a phage particle capsid (right image). The particles investigated here are dynamic capsid II expansion products that potentially mature to become capsids of phages; arrows in the third image from the left indicate expansion/contraction dynamism. Although pictured here as intermediates, intermediate status has not been biochemically demonstrated for particles generated by shell dynamism.