Distribution of world haplogroups in the Timorese sample

Autor/Urheber:

Margaux A. Morrison, Tiago R. Magalhaes, Jacqueline Ramke, Silvia E. Smith, Sean Ennis, Claire L. Simpson, Laura Portas, Federico Murgia, Jeeyun Ahn, Caitlin Dardenne, Katie Mayne, Rosann Robinson, Denise J. Morgan, Garry Brian, Lucy Lee, Se J. Woo, Fani Zacharaki, Evangelia E. Tsironi, Joan W. Miller, Ivana K. Kim, Kyu H. Park, Joan E. Bailey-Wilson, Lindsay A. Farrer, Dwight Stambolian and Margaret M. DeAngelis

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Beschreibung:

Distribution of world haplogroups in the Timorese sample. (A) Distribution of the Y-STR haplogroups among males. (B) Distribution of the mtDNA haplogroups. Populations are shown according to color.

The Y-STR analysis yielded genotypes for 265 of the 267 Timorese males. Using the publicly available databases World Haplogroup & Haplo-I Subclade Predictor[1] and Althey's Haplogroup Predictor[2], 11 haplogroups were assigned to 248 of these subjects. The origin of the haplogroups is mostly Asia (73%), followed by Africa and Eurasia (13% each), and a small percent Oceana (1%).

MtDNA genotypes were determined for all 535 Timorese subjects using the publicly available reference data and are distributed among 14 haplogroups. The haplogroups distribution shows that the origin of the Timorese males is mostly Asian (69%), followed by Oceanic (17%), African (13%), and a small percent Eurasian (1%). Given the within-group diversity present, it is likely that either multiple migrations or a few migrations of distantly related male individuals from Asia and other parts of the Old World have populated the islands, which is consistent with pre-historical and historical events.

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CC BY 4.0

Credit:

Morrison MA, Magalhaes TR, Ramke J, Smith SE, Ennis S, Simpson CL, Portas L, Murgia F, Ahn J, Dardenne C, Mayne K, Robinson R, Morgan DJ, Brian G, Lee L, Woo SJ, Zacharaki F, Tsironi EE, Miller JW, Kim IK, Park KH, Bailey-Wilson JE, Farrer LA, Stambolian D and DeAngelis MM (2015) Ancestry of the Timorese: age-related macular degeneration associated genotype and allele sharing among human populations from throughout the world. Front. Genet. 6:238. doi: 10.3389/fgene.2015.00238 http://journal.frontiersin.org/article/10.3389/fgene.2015.00238/full

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